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KMID : 0191120100250071029
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Journal of Korean Medical Science
2010 Volume.25 No. 7 p.1029 ~ p.1033
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Detection of Recurrence by 18F-FDG PET in Patients with Endometrial Cancer Showing No Evidence of Disease
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Ryu Sang-Young
Kim Ki-Dong
Kim Youn-Ha
Park Sang-Il
Kim Beob-Jong
Kim Moon-Hong
Choi Seok-Cheol
Lee Eui-Don
Lee Kyung-Hee
Kim Byung-Il
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Abstract
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This study assessed the feasibility of F-18-fluorodeoxyglucose positron-emission tomography (18F-FDG PET) in the post-therapy surveillance for patients with endometrial cancer showing no evidence of disease (NED). From April 1997 to June 2007, 127 patients with endometrial cancer showing NED were performed 18F-FDG PET scan. The feasibility of 18F-FDG PET for the early detection of recurrence in patients with endometrial cancer was evaluated retrospectively. Of the 127 patients, 32 patients showed positive lesions on 18F-FDG PET scan. Nineteen (19/127 cases, 15%) of them were confirmed to have a recurrence clinically or histologically. The sensitivity, specificity and positive and negative predictive value of 18F-FDG PET for detecting recurrences in patients with endometrial cancer were 100%, 88%, 59% and 100%, respectively. In conclusion, 18F-FDG PET may be a useful method for the post-therapy surveillance in patients with endometrial cancer.
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KEYWORD
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Endometrial Neoplasms, Recurrence, Positron-Emission Tomography
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